Human Immunodeficiency Virus (HIV) Cervicovaginal Shedding During the Menstrual Cycle in Seropositive Women Followed at a Specialized Care Center in São Paulo
Year: 2008
Type: article
Study design: Observational Study
Abstract: The sexual route is the main means of transmission of the human immunodeficiency virus (HIV). With the increasing numbers of HIV-infected women, the investigation of particular biological features of HIV infection in the genital tract has become more important. To evaluate HIV genital shedding during the menstrual cycle, we collected cervicovaginal lavages (CVL) from 17 women, assisted at an HIV outpatient clinic in São Paulo, in different hormonal phases during 2 cycles. HIV-RNA and proviral DNA shedding were quantified using RT-PCR and a TaqMan real-time PCR assay, respectively.
Institutions: Universidade de São Paulo, Boston University, Rush University
Language: English
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,900
OpenAlex ID: W2010815939