Sialic Acids on the Plasma Membrane of Cultured Human Lymphoid Cells
Year: 1972
Type: article
Abstract: From 61 to 92% of the total sialic acid of a variety of human lymphoid cell lines maintained in tissue culture is present on the cell surface as measured by its susceptibility to cleavage by Clostridium perfringens neuraminidase. These cells contain from 1.22 x 10(8) to 6.99 x 10(8) molecules of surface sialic acid per cell. In synchronized cultures synthesis of surface sialic acid occurs only during a limited time in the late G(2) phase of the cell cycle. The amount and density of surface sialic acid vary considerably throughout the cell cycle.
Source: The Journal of Cell Biology
DOI: 10.1083/jcb.53.2.466
Authors: Steven A. Rosenberg, Albert B. Einstein
Institutions: National Institutes of Health, National Cancer Institute
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2011053586