Work

High frequency asynchronous magnetic bead rotation for improved biosensors

Year: 2010

Type: article

Abstract: Biosensors with increasingly high sensitivity are crucial for probing small scale properties. The asynchronous magnetic bead rotation (AMBR) sensor is an emerging sensor platform, based on magnetically actuated rotation. Here the frequency dependence of the AMBR sensor's sensitivity is investigated. An asynchronous rotation frequency of 145 Hz is achieved. This increased frequency will allow for a calculated detection limit of as little as a 59 nm change in bead diameter, which is a dramatic improvement over previous AMBR sensors and further enables physical and biomedical applications.

Source: Applied Physics Letters

DOI: 10.1063/1.3505492

Authors: Paivo Kinnunen, Irene Sinn, Brandon H. McNaughton, Raoul Kopelman

Institution: University of Michigan

Language: English

Topic: Characterization and Applications of Magnetic Nanoparticles

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: bronze