Year: 1974
Type: article
Abstract: Time-space “clusters” of leukemia cases have been reported since the 1930s; since 1960, a great number of such observations has been made. However, it is still an open question whether or not the phenomenon is real.5 “Clustering” of Hodgkin's disease cases is a relatively new phenomenon.6,17,18 The reports appear more convincing than those relating to leukemia, but closer analysis reveals possible serious methodological flaws which make their interpretation difficult. In this paper we consider the currently more interesting Hodgkin's disease situation, using the leukemia studies as a guide as to what pitfalls should be avoided. We then reverse the process and suggest cluster studies that should now be conducted in leukemia on the basis of what may be learned from the Hodgkin's disease studies.
Source: Cancer
Authors: M. C. Pike, P. G. Smith
Institutions: University of Southern California, University of Oxford
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2011558225