Work

Role of transposable elements in age-related genomic instability

Year: 1997

Type: review

Abstract: Genetic instability is associated with aging in many species. One of the initiating factors for genetic instability is the movement of transposable elements (TEs), which occur in all prokaryotic and eukaryotic organisms. The hypothesis that TEs could be involved in the aging process is discussed and the correlation between aging and activity of TEs is analysed in a variety of biological systems.

Source: Genetics Research

DOI: 10.1017/s0016672397002772

Authors: A. G. NIKITIN, R. J. SHMOOKLER REIS

Institutions: University of Arkansas for Medical Sciences, John L. McClellan Memorial Veterans Hospital

Language: English

Topic: Chromosomal and Genetic Variations

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: bronze

Funders: Bowling Green State University, National Institutes of Health, National Institute on Aging

Awards: POLYMORPHIC GENES MODULATING LIFESPAN IN C ELEGANS, G615400020