Year: 2010
Type: review
Abstract: Lipid droplets (LDs) were perceived as static storage deposits, which passively participate in the energy homeostasis of both cells and entire organisms. However, this view has changed recently after the realization of a complex and highly dynamic LD proteome. The proteome contains key components of the fat mobilization system and proteins that suggest LD interactions with a variety of cell organelles, including the endoplasmic reticulum, mitochondria and peroxisomes. The study of LD cell biology, including cross-talk with other organelles, the trafficking of LDs in the cell and regulatory events involving the LD coat proteins is now on the verge of leaving its infancy and unfolds that LDs are highly dynamic cellular organelles.
Source: FEBS Letters
Institution: Max Planck Institute for Biophysical Chemistry
Language: English
Subfield: Biochemistry
Domain: Life Sciences
Open Access status: bronze
Funder: Max-Planck-Gesellschaft
OpenAlex ID: W2012296410