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Htm1p: getting a “sugar-handle” on misfolded proteins

Year: 2009

Type: article

Abstract: ![Graphic][1] Htm1p produces Man7GlcNAc2, which Yos9p can recognize by its exposed α1,6-mannose ring (circled). [Clerc et al.][2] show that the yeast protein Htm1p flags misfolded secretory proteins for degradation. When first inserted into the endoplasmic reticulum (ER), proteins

Source: The Journal of Cell Biology

DOI: 10.1083/jcb.1841iti3

Author: Caitlin Sedwick

Language: English

Topic: Endoplasmic Reticulum Stress and Disease

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2012375465

FWCI:

Cites: 1

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Related to: 10