Systemic delivery of TLR9-activating/STAT3-blocking oligonucleotides induces leukemia regression
Year: 2014
Type: conference-abstract
Abstract: Meeting abstracts Inhibition of transcription factors (TF) that drive tumor progression and immune evasion, such as STAT3, remains a challenge for pharmacological drugs. Blocking STAT3 binding to DNA using specific decoy oligodeoxynucleotides (dODN) provides an alternative targeted inhibitory
Institutions: City Of Hope National Medical Center, City of Hope
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W2012866196