Work

Regioselective Enzymatic Carboxylation of Phenols and Hydroxystyrene Derivatives

Year: 2012

Type: article

Abstract: The enzymatic carboxylation of phenol and styrene derivatives using (de)carboxylases in carbonate buffer proceeded in a highly regioselective fashion: Benzoic acid (de)carboxylases selectively formed o-hydroxybenzoic acid derivatives, phenolic acid (de)carboxylases selectively acted at the β-carbon atom of styrenes forming (E)-cinnamic acids.

Source: Organic Letters

DOI: 10.1021/ol300385k

Authors: Christiane Wuensch, Silvia M. Glueck, Johannes Gross, Dominik Koszelewski, Markus Schober, Kurt Faber

Institutions: University of Graz, Austrian Centre of Industrial Biotechnology (Austria)

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $1,680

Funders: Austrian Federal Ministry of Economy, Family and Youth, Bundesministerium für Verkehr, Innovation und Technologie, Austrian Centre of Industrial Biotechnology