Work

Stimulated Raman scattering imaging by continuous-wave laser excitation

Year: 2013

Type: article

Abstract: We demonstrate a low-cost-stimulated Raman scattering (SRS) microscope using continuous-wave (cw) lasers as excitation sources. A dual modulation scheme is used to remove the electronic background. The cw-SRS imaging of lipids in fatty liver is demonstrated by excitation of C─H stretch vibration.

Source: Optics Letters

DOI: 10.1364/ol.38.001479

Authors: Chun-Rui Hu, Mikhail N. Slipchenko, Ping Wang, Pu Wang, Jiandie D. Lin, Garth Simpson, Bing Hu, Ji-Xin Cheng

Institutions: University of Science and Technology of China, Purdue University West Lafayette, University of Michigan, Michigan Medicine

Language: English

Topic: Spectroscopy Techniques in Biomedical and Chemical Research

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Biomedical Imaging and Bioengineering

Awards: G2008391963, G301048564, G450272272, Autophagy in hepatic lipid metabolism and disease, Nonlinear Optical Imaging for Guiding Protein Structure Determination

OpenAlex ID: W2014231580

FWCI: 3.037

Cites: 15

Cited by: 39

Related to: 10