Work

Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive rats

Year: 2010

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2010.07.014

Authors: John D. Ginn, Todd Bosanac, Rhonda Chen, Charles Cywin, Eugene Hickey, Mohammed Kashem, Steven Kerr, Stanley Kugler, Xiang Li, Anthony Prokopowicz, Sabine Schlyer, James D. Smith, Michael R. Turner, Frank Wu, Erick R.R. Young

Institution: Boehringer Ingelheim (United States)

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2014400072

FWCI: 0.781

Cites: 25

Cited by: 23

Related to: 10