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Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload

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Year: 2013
Type: article
Source: Free Radical Biology and Medicine
DOI: 10.1016/j.freeradbiomed.2013.09.008
Authors: Kelsey H. Fisher-Wellman, Laura A.A. Gilliam, Chien-Te Lin, Brook L. Cathey, Daniel S. Lark, P. Darrell Neufer
Institution: East Carolina University
Language: English

Topic: Redox biology and oxidative stress
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, U.S. Public Health Service, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Awards: The role of mitochondria in skeletal muscle fatigue caused by cancer chemotherapy, Redox Biology and Muscle Insulin Sensitivity, G4400525289, G620140367, Linking Mitochondrial Bioenergetics to Muscle Insulin Sensitivity, G7241364570
OpenAlex ID: W2014538367
FWCI: 4.177
Cites: 30
Cited by: 115
Related to: 10
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