Work

Frequency of functional drug disposition gene polymorphism in Thai population: relevance to antiretroviral drugs

Year: 2008

Type: conference-abstract

Abstract: Purpose of the study Significantly higher plasma exposure of some protease inhibitors (PIs) has been observed in Thai subjects compared to Caucasians. These differences may partially be explained by factors such as body weight and diet. However, pharmacogenetic differences may also contribute. The aim of this study was to investigate, in a Thai population, the frequency of functional polymorphisms in genes known to influence plasma concentrations of antiretroviral drugs.

Source: Journal of the International AIDS Society

DOI: 10.1186/1758-2652-11-s1-p237

Authors: A Chaikan, N Chierakul, N Saguenwong, C Chuchuttaworn, A Owen, L Dickinson, SH Khoo, DJ Back, GR Davies

Institutions: University of Liverpool, Siriraj Hospital, Bamrasnaradura Infectious Diseases Institute

Language: English

Topic: Pharmacogenetics and Drug Metabolism

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,600

OpenAlex ID: W2014762236

Cites:

Cited by: 3

Related to: 10