Year: 1986
Type: article
Abstract: probably accelerated the fatal course in one of them.' The same cause might explain the outcome in other cases of fatal side effects of valproate.'The families ofsuch children need to be investigated because (a) a common cause offatal valproate toxicity might be found, (b) a procedure to detect people at risk might be advised-for example, measuring plasma ammonia concentra- tions for initial monitoring oftreatment-and (c) confidence about using the drug for children and adults without a metabolic abnormality might be restored.I Rolles CJ.Hepatic injury with sodium valproate:a reappraisal with special reference tochildren.Br
Source: BMJ
Institution: Southampton General Hospital
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2014884076