Work

Full-Wave Iterative Image Reconstruction in Photoacoustic Tomography With Acoustically Inhomogeneous Media

Year: 2013

Type: article

Abstract: Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the effects of measurement data incompleteness and noise. In this work, we develop and investigate a discrete imaging model for PACT that is based on the exact photoacoustic (PA) wave equation and facilitates the circumvention of these limitations. A key contribution of the work is the establishment of a procedure to implement a matched forward and backprojection operator pair associated with the discrete imaging model, which permits application of a wide-range of modern image reconstruction algorithms that can mitigate the effects of data incompleteness and noise. The forward and backprojection operators are based on the k-space pseudospectral method for computing numerical solutions to the PA wave equation in the time domain. The developed reconstruction methodology is investigated by use of both computer-simulated and experimental PACT measurement data.

Source: IEEE Transactions on Medical Imaging

DOI: 10.1109/tmi.2013.2254496

Authors: Chao Huang, Kun Wang, Liming Nie, Lihong V. Wang, Mark A. Anastasio

Institution: Washington University in St. Louis

Language: English

Topic: Photoacoustic and Ultrasonic Imaging

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering

Awards: G1336003130, G7006692143, G9000153293