Challenges and Opportunities in dermal/transdermal Delivery
Year: 2010
Type: review
Abstract: Transdermal drug delivery is an exciting and challenging area. There are numerous transdermal delivery systems currently available on the market. However, the transdermal market still remains limited to a narrow range of drugs. Further advances in transdermal delivery depend on the ability to overcome the challenges faced regarding the permeation and skin irritation of the drug molecules. Emergence of novel techniques for skin permeation enhancement and development of methods to lessen skin irritation would widen the transdermal market for hydrophilic compounds, macromolecules and conventional drugs for new therapeutic indications. As evident from the ongoing clinical trials of a wide variety of drugs for various clinical conditions, there is a great future for transdermal delivery of drugs.
Source: Therapeutic Delivery
DOI: 10.4155/tde.10.16
Institution: University of Kentucky
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
Funder: National Institute on Drug Abuse
Awards: Clinical Evaluation of Novel Methods for Extending Microneedle Pore Lifetime, Naltrexone Prodrugs for Transdermal Delivery, Transdermal Cannabinoid Prodrug Treatment for Cannabis Withdrawal and Dependence, Transdermal Delivery of Buprenorphine Prodrugs, Transdermal Delivery of Hydroxyphenylarachidonylamides, Gated Carbon Nanotube Membrane Transdermal Drug Delivery
OpenAlex ID: W2016181184