Work

87: Peripheral Blood Stem Cell Transplant for POEMS Syndrome is Associated with High Rates of Engraftment Syndrome

Year: 2008

Type: article

Abstract: Background: POEMS syndrome is a devastating syndrome, characterized by peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasma cells, skin changes, papilledema, volume overload, sclerotic bone lesions, thrombocytosis, and high VEGF. High-dose chemotherapy with autologous peripheral blood stem cell transplantation (ASCT) ultimately yields excellent clinical responses, but there can be considerable peri-transplant morbidity. Methods: Thirty patients with POEMS syndrome have been treated with PBSCT at the Mayo Clinic Rochester, 11 of whom have been previously reported.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2007.12.096