Work

Larvicidal, Antimycobacterial and Antifungal Compounds from the Bark of the Peruvian Plant Swartzia polyphylla DC

Year: 2006

Type: article

Abstract: The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.54.278

Authors: Rosario Rojas, Betty Bustamante, Palmira Ventosilla, Irma Fernádez, Luz Caviedes, Robert Henry Gilman, Olga Lock, Gerald Bruce Hammond

Institutions: Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Johns Hopkins University, Pontificia Universidad Católica del Perú, University of Louisville

Language: English

Topic: Phytochemical compounds biological activities

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: University of Louisville, CYTED Ciencia y Tecnología para el Desarrollo, Pontificia Universidad Católica del Perú, Universidad de Salamanca

OpenAlex ID: W2017003218

FWCI: 0.815

Cites: 16

Cited by: 33

Related to: 10