Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Work
Year: 2008
Type: article
Abstract: Tumors contain oxygenated and hypoxic regions, so the tumor cell population is heterogeneous. Hypoxic tumor cells primarily use glucose for glycolytic energy production and release lactic acid, creati... more
Institutions UCLouvain, Duke Medical Center, Duke University Hospital
Cites: 56
Cited by: 1,537
Related to: 10
FWCI: 17.35
Citation percentile (by year/subfield): 99.98
Subfield: Cancer Research
Domain: Life Sciences
Sustainable Development Goal Affordable and clean energy
Open Access status: bronze