Work

Recipient T-Cell Repertoire Diversity after Double Umbilical Cord Transplantation Correlates with Non-Relapse Mortality and Survival

Year: 2014

Type: article

Abstract: Complications of allogeneic stem cell transplant, such as infection, relapse and GvHD, are linked to failure of balanced immune reconstitution. Early quantification of immunologic function is crucial to identify those at risk and institute pre-emptive therapies. We hypothesize that T-cell receptor (TCR) diversity after double umbilical cord blood transplantation (dUCBT) will predict clinical outcomes.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2013.12.409