Work

Reduced risk of synovial sarcoma in females: X-chromosome inactivation?

Year: 2002

Type: article

Abstract: Synovial sarcoma shows a characteristic t(X;18) translocation but not the expected female predominance in incidence. We speculate that, among females, one X-chromosome is inactivated and that only the translocation to an active X-chromosome leads to development of synovial sarcoma. Population-based cancer registry data from the SEER program support this hypothesis.

Source: British Journal of Cancer

DOI: 10.1038/sj.bjc.6600362

Authors: X Bu, L Bernstein, R K Brynes

Institution: University of Southern California

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,190