Work

Magnetic‐Field‐Assisted Electrospinning of Aligned Straight and Wavy Polymeric Nanofibers

Year: 2010

Type: article

Abstract: Aligned straight and wavy fibers of biodegradable poly(D,L-lactic-co-glycolic acid) (PLGA) are fabricated using a magnetic-field-assisted electrospinning method. PLGA fibrous matrices prepared by this method can guide the growth of pluripotent murine mesenchymal stem cells. While the stem cells on the randomly oriented fibers adapt pseudo-sphere-like shape, those on aligned fibers exhibit elongated morphology along the long axes (see figure).

Source: Advanced Materials

DOI: 10.1002/adma.200903870

Authors: Yaqing Liu, Xinping Zhang, Younan Xia, Hong Yang

Institutions: North University of China, University of Rochester, University of Rochester Medicine, Washington University in St. Louis

Language: English

Topic: Electrospun Nanofibers in Biomedical Applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funders: National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Center for Research Resources

Awards: The University of Rochester Clinical and Translational Science Institute, Angiogenesis & Osteogenesis in Structural Graft Healing