Work

Modern Natural Products Drug Discovery and Its Relevance to Biodiversity Conservation

Year: 2010

Type: review

Abstract: Natural products continue to provide a diverse and unique source of bioactive lead compounds for drug discovery, but maintaining their continued eminence as source compounds is challenging in the face of the changing face of the pharmaceutical industry and the changing nature of biodiversity prospecting brought about by the Convention on Biological Diversity. This review provides an overview of some of these challenges and suggests ways in which they can be addressed so that natural products research can remain a viable and productive route to drug discovery. Results from International Cooperative Biodiversity Groups (ICBGs) working in Madagascar, Panama, and Suriname are used as examples of what can be achieved when biodiversity conservation is linked to drug discovery.

Source: Journal of Natural Products

DOI: 10.1021/np100550t

Author: David G. I. Kingston

Institution: Virginia Tech

Language: English

Topic: Ethnobotanical and Medicinal Plants Studies

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Life on land

Open Access status: green

Funder: Fogarty International Center