Work

A Critical Appraisal of the Hippocampal Subfield Segmentation Package in FreeSurfer

Year: 2014

Type: article

Abstract: In the last decade, the in vivo assessment of hippocampal subfields has received increasing attention because of the differ-ential role of hippocampal subfields in sev-eral neuropsychiatric diseases (Geuze et al., 2005). Several manual segmentation pro-tocols have been developed for 3–7 T MRI (Mueller et al., 2007; Van Leemput et al., 2008; La Joie et al., 2010; Wisse et al., 2012), some of which are automated (Van Leem-put et al., 2008; Yushkevich et al., 2009). One of these automated protocols (Van Leemput et al., 2008, 2009) has recently been implemented in FreeSurfer (Fischl, 2012), a freely available easy-to-use set of automated brain MRI analysis tools. This has made hippocampal subfield segmen-tation available to everyone with 1.5–3 T MRI data and the method is being used in an increasing number of studies (Teicher

Source: Frontiers in Aging Neuroscience

DOI: 10.3389/fnagi.2014.00261

Authors: Laura E. M. Wisse, Geert Jan Biessels, Mirjam I. Geerlings

Institution: University Medical Center Utrecht

Language: English

Topic: Medical Image Segmentation Techniques

Subfield: Computer Vision and Pattern Recognition

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801