Work

Chemically Functionalized Carbon Nanotubes as Substrates for Neuronal Growth

Year: 2004

Type: article

Abstract: We report the use of chemically modified carbon nanotubes as a substrate for cultured neurons. The morphological features of neurons that directly reflect their potential capability in synaptic transmission are characterized. The chemical properties of carbon nanotubes are systematically varied by attaching different functional groups that confer known characteristics to the substrate. By manipulating the charge carried by functionalized carbon nanotubes we are able to control the outgrowth and branching pattern of neuronal processes.

Source: Nano Letters

DOI: 10.1021/nl035193d

Authors: Hui Hu, Yingchun Ni, Vedrana Montana, Robert C. Haddon, Vladimir Parpura

Institution: University of California, Riverside

Language: English

Topic: Neuroscience and Neural Engineering

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: green

Funder: National Institute of Mental Health

Award: Calcium-dependent glutamate release from astrocytes