Year: 2011
Type: article
Abstract: One third of all breast cancers are diagnosed in women aged 70 or over. Older women are a heterogeneous population who are under-represented in clinical trials, and as a result uncertainty can exist as to what represents optimal treatment. This minireview, from an international authorship, summarises the existing evidence surrounding the management of early breast cancer in women aged 70 and over. The use of primary surgery and endocrine therapy, and adjuvant chemotherapy, radiotherapy, endocrine therapy and trastuzumab are discussed. Reference is made to ongoing clinical trials in this area and areas of controversy are highlighted.
Source: British Journal of Cancer
DOI: 10.1038/bjc.2011.234
Institutions: Brighton and Sussex Medical School, Royal Sussex County Hospital, University of Sheffield, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Western General Hospital, Edinburgh Cancer Research, University of Edinburgh, UNC Lineberger Comprehensive Cancer Center, Universitair Ziekenhuis Leuven, KU Leuven, Cancer Research UK, The Royal Free Hospital
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $5,190
OpenAlex ID: W2019311984