Year: 1999
Type: article
Abstract: The transport and sorting of proteins newly made in the endoplasmic reticulum (ER) has long been a fascinating and contentious issue to those interested in membrane traffic processes. Secretory and membrane proteins, collectively termed “cargo proteins,” exit the ER in vesicles targeted to the Golgi apparatus. Transport through the Golgi is often accompanied by extensive posttranslational modification until the trans-Golgi network (TGN) is reached. Here, cargo is sorted into vesicles bound for different destinations including secretory granules, the plasma membrane, and the endosome/lysosome system.
Source: Cell
Authors: Graham Warren, Ira Mellman
Institution: Yale University
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $11,400
OpenAlex ID: W2020857417