Work

Preeclampsia and Adiponectin in Cord Blood

Year: 2010

Type: article

Abstract: AIMS: To compare cord blood concentrations of total adiponectin in the offspring of pregnancies with and without preeclampsia. METHODS: Using a Luminex analyzer, cord blood adiponectin was measured in 182 singleton pregnancies with preeclampsia and compared to adiponectin measured in 511 singleton pregnancies without preeclampsia. RESULTS: Adiponectin levels in cord blood increased with increasing gestational age, but overall, crude levels were similar in pregnancies with and without preeclampsia. However, in pregnancies with early delivery (weeks 32-36), and in pregnancies with delivery after spontaneous contractions, adiponectin levels were higher in the preeclampsia group. CONCLUSION: In preterm pregnancies and in pregnancies with spontaneous contractions, adiponectin levels in cord blood were higher in the preeclampsia group than in pregnancies without preeclampsia, maybe reflecting the need to optimize energy in preeclampsia.

Source: Hormone Research in Paediatrics

DOI: 10.1159/000313376

Authors: Bjorn Ogland, Pål R. Romundstad, Hege Vefring, Michele R. Forman, Stein Tore Nilsen, Lars J. Vatten

Institutions: Norwegian University of Science and Technology, The University of Texas MD Anderson Cancer Center, Stavanger University Hospital

Language: English

Topic: Pregnancy and preeclampsia studies

Subfield: Obstetrics and Gynecology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute