Work

Structure-based mutagenesis of the integrase-LEDGF/p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness

Year: 2006

Type: article

Source: Virology

DOI: 10.1016/j.virol.2006.08.011

Authors: Shaila Rahman, Richard Lu, Nick Vandegraaff, Peter Cherepanov, Alan Engelman

Institutions: Dana-Farber Cancer Institute, Harvard University, Imperial College London

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, Center for AIDS Research, University of Washington, National Institute of Allergy and Infectious Diseases

Awards: G1395504825, G1872198807, G2994024037, Integrase Structural Virology, HIV-1 Preintegration Trafficking and Nuclear Localization, Harvard University Center for AIDS Research

OpenAlex ID: W2021030434

FWCI: 2.559

Cites: 64

Cited by: 64

Related to: 10