Work

Heat capacity and entropy changes in processes involving proteins.

Year: 1977

Type: article

Abstract: Six possible sources of the large heat capacity and entropy changes frequently observed for processes involving proteins are identified. Of these the conformational, hydrophobic, and vibrational effects seem likely to be of greatest importance. A method is proposed for estimating the magnitudes of the hydrophobic and vibrational contributions. Application of this method to several protein processes appears to achieve significant clarification of previously confusing and apparently contradictory data.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.74.6.2236

Author: J M Sturtevant

Institution: Yale University

Language: English

Topic: thermodynamics and calorimetric analyses

Subfield: Physical and Theoretical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2021163287

FWCI: 7.222

Cites: 38

Cited by: 858

Related to: 10