Impact of HLA-Mismatch in Unrelated Donor Hematopoietic Stem Cell Transplantation: A Comprehensive Meta-Analysis
Year: 2015
Type: article
Study designs: Systematic Review, Meta-Analysis
Abstract: Mismatched unrelated donor (MMURD) transplantation is widely used in patients who lack a matched unrelated donor (MUD). Despite several published observational studies, the magnitude of risk associated with 9 out of 10 MMURD transplant and that of HLA-specific mismatches is still unclear. We performed a meta-analysis to assess the difference in outcomes of MUD to those of MMURD transplant.
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2021817257
