Work

What’s New About Osmotic Regulation of Glycerophosphocholine

Year: 2009

Type: article

Abstract: Glycerophosphocholine is an abundant renal medullary organic osmolyte that protects renal medullary cells from the high interstitial concentrations of NaCl and urea to which they are normally exposed. We consider the metabolism of glycerophosphocholine, its osmotic regulation, and the recently discovered molecular identity of the enzymes that osmoregulate its abundance.

Source: Physiology

DOI: 10.1152/physiol.00009.2009

Authors: Morgan Gallazzini, Maurice B. Burg

Institutions: National Institutes of Health, National Heart, Lung, and Blood Institute

Language: English

Topic: Ion Transport and Channel Regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute

Award: Response Of Renal Cells To Osmotic Stress