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Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment

Year: 2014
Type: conference-abstract
Abstract: Meeting abstracts The underlying cause for the failure of immune checkpoint blockade is the overwhelming, persistent and multifocal immune suppression in the tumor microenvironment. This is due to the absence of pre-existing antitumor Teff because of the action of important upstream immune
DOI: 10.1186/2051-1426-2-s3-p266
Authors: Adam Yopp, Nikoletta Kallinteris, Xianming Huang, Joe Shan, Kerstin Menander, Bruce Freimark, Jeff Hutchins, Steve King, Dmitry I Gabrilovich, Rolf Brekken
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W2023211059
Cites:
Cited by: 1
Related to: 10