Work

Arabidopsis thaliana MTP1 is a Zn transporter in the vacuolar membrane which mediates Zn detoxification and drives leaf Zn accumulation

Year: 2005

Type: article

Abstract: The Arabidopsis thaliana metal tolerance protein 1 (MTP1) of the cation diffusion facilitator family of membrane transport proteins can mediate the detoxification of Zn in Arabidopsis and yeast. Xenopus laevis oocytes expressing AtMTP1 accumulate more Zn than oocytes expressing the AtMTP1(D94A) mutant or water-injected oocytes. An AtMTP1-GFP fusion protein localizes to the vacuolar membrane in root and leaf cells. The analysis of Arabidopsis transformed with a promoter-GUS construct suggests that AtMTP1 is not produced throughout the plant, but primarily in the subpopulation of dividing, differentiating and expanding cells. RNA interference-mediated silencing of AtMTP1 causes Zn hypersensitivity and a reduction in Zn concentrations in vegetative plant tissues.

Source: FEBS Letters

DOI: 10.1016/j.febslet.2005.06.046

Authors: Anne-Garlonn Desbrosses-Fonrouge, Katrin Voigt, Astrid Schröder, Stéphanie Arrivault, Sébastien Thomine, Ute Krämer

Institutions: Max Planck Institute of Molecular Plant Physiology, Max Planck Society, Centre National de la Recherche Scientifique, Institut des Sciences du Végétal

Language: English

Topic: Plant Micronutrient Interactions and Effects

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Zero hunger

Open Access status: bronze

Funders: Deutscher Akademischer Austauschdienst, Deutsche Forschungsgemeinschaft, Bundesministerium für Bildung und Forschung