Body mass index through life and adult mortality: results from the British 1946 birth cohort
Year: 2009
Type: conference-abstract
Abstract: Results: In terms of incidence, in 1980, the overall ASR varied widely across countries, ranging from 18 per 100 000 in Belarus to 309 per 100 000 in Switzerland.Between 1980 and 2002, prostate cancer incidence increased in all 20 countries.The OPC was the smallest in Denmark (+40%) and highest in Italy (+336%).Generally, countries with lower incidence in early years had the highest OPCs.In North-America and Australia incidence peaked around 1994, whereas in most European countries rates rose throughout the study period.The increase was most pronounced among men aged 50-74, and in a few countries, the OPC for men aged >75 years was less than zero.Mortality rates decreased in North-America and some western European countries (eg France, England, Italy, Switzerland), remained stable in others (eg Scotland, Sweden, Denmark) and increased in Eastern Europe.In countries where rates fell, the decline was more pronounced among younger, than older, men.In some countries (eg France), mortality began to fall before incidence peaked.Conclusions: International variations in prostate cancer incidence and mortality were observed.The different trend in incidence by age suggests an impact of earlier diagnosis/PSA testing.While the decreases in mortality observed in some countries might be a result of improvements in treatment or earlier detection, they could also be affected by changes in death certificate coding or competing causes of death.
Authors: B. H. Strand, D. Kuh, I. Shah, J. Guralnik, R. Hardy
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2024513644