Work

A Diazirine-Based Nucleoside Analogue for Efficient DNA Interstrand Photocross-Linking

Year: 2008

Type: article

Abstract: A diazirine-based nucleoside analogue (DBN) efficiently forms DNA interstand cross-linking under near-UV irradiation. This new base analogue may find broad applications in biotechnology and phototherapy.

Source: Journal of the American Chemical Society

DOI: 10.1021/ja805445j

Authors: Zhihai Qiu, Lianghua Lu, Xing Jian, Chuan He

Institution: University of Chicago

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Direct Oxidative Nucleic Acids Demethylation

OpenAlex ID: W2024869506

FWCI: 1.781

Cites: 28

Cited by: 73

Related to: 10