Year: 2002
Type: article
Abstract: An unprecedented wealth of biological data has been generated by the human genome project and sequencing projects in other organisms.The huge demand for analysis and interpretation of these data is being managed by the evolving science of bioinformatics.Bioinformatics is defined as the application of tools of computation and analysis to the capture and interpretation of biological data.It is an interdisciplinary field, which harnesses computer science, mathematics, physics, and biology (fig 1).Bioinformatics is essential for management of data in modern biology and medicine.This paper describes the main tools of the bioinformatician and discusses how they are being used to interpret biological data and to further understanding of disease.The potential clinical applications of these data in drug discovery and development are also discussed. MethodsThis article is based on personal experience in bioinformatics and on selected articles in recent issues of Nature Genetics, Nature Genetics Reviews, Nature Medicine, and Science.Key terms including bioinformatics, comparative and functional genomics, proteomics, microarray, disease, and medicine were used to search for relevant articles in the peer reviewed scientific literature.
Source: BMJ
Author: Ardeshir Bayat
Institution: University of Manchester
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2025004204