Work

Determinants of SR protein specificity

Year: 1999

Type: article

Abstract: The SR (Ser-Arg) proteins are a family of nuclear factors that play multiple important roles in splicing of mRNA precursors in metazoan organisms, functioning in both constitutive and regulated splicing. Certain of these functions are redundant, such that any single SR proteins will suffice, but other functions are unique and are specific to a given family member. A number of studies during the past year have investigated the basis for SR protein specificity.

Source: Current Opinion in Cell Biology

DOI: 10.1016/s0955-0674(99)80050-7

Authors: Roland Tacke, James L Manley

Institution: Columbia University

Language: English

Topic: RNA Research and Splicing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $4,390

Funder: U.S. Public Health Service