Work

Rhodium-Catalyzed Chemo- and Regioselective Cross-Dimerization of Two Terminal Alkynes

Year: 2013

Type: article

Abstract: Cross-dimerization of terminal arylacetylenes and terminal propargylic alcohols/amides has been achieved in the presence of a rhodium catalyst. This method features high chemo- and regioselectivities rendering convenient and atom economical access to functionalized enynes.

Source: Organic Letters

DOI: 10.1021/ol303531m

Authors: Hua-Dong Xu, Ren-Wei Zhang, Xiaoxun Li, Suyu Huang, Weiping Tang, Wen-Hao Hu

Institutions: University of Wisconsin–Madison, Changzhou University, East China Normal University

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Development of Cyclopropyl Metal Carbene Based Methods for Organic Synthesis