Work

Direct Ex Vivo Measurement of CD8+T-Lymphocyte Responses to Human Parvovirus B19

Year: 2001

Type: article

Abstract: Parvovirus B19 is a common human pathogen which can cause severe syndromes, including aplastic anemia and fetal hydrops. The mapping of the first parvovirus B19-derived CD8(+) T-lymphocyte epitope is described. This HLA-B35-restricted peptide derives from the nonstructural (NS1) protein and is strongly immunogenic in B19 virus-seropositive donors.

Source: Journal of Virology

DOI: 10.1128/jvi.75.1.540-543.2001

Authors: T. Tolfvenstam, A. Oxenius, D. A. Price, B. L. Shacklett, H. M. L. Spiegel, K. Hedman, O. Norbeck, M. Levi, K. Olsen, M. Kantzanou, D. F. Nixon, K. Broliden, P. Klenerman

Institutions: Karolinska Institutet, John Radcliffe Hospital, Aaron Diamond AIDS Research Center, Rockefeller University, University of Helsinki

Language: English

Topic: Parvovirus B19 Infection Studies

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of Allergy and Infectious Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G23400721, G2513169187, PATHOGENESIS OF PEDIATRIC HIV INFECTION, DYNAMICS OF HIV1 SPECIFIC CTL IN HIV1 INFECTION, Understanding and Altering the Virologic Setpoint, G841415025

OpenAlex ID: W2026070354

FWCI: 2.649

Cites: 36

Cited by: 45

Related to: 10