Immune Reconstitution (IR) Following Unrelated Cord Blood Transplantation (UCBT) In Pediatric Recipients: Reduced Toxicity Conditioning (RTC) Is Associated With Similar IR But A Concomitant Significant Decrease In Grade II-IV Acute Graft Versus Host Disease (AGVHD) Compared To Myeloablative Conditioning (MAC)
Year: 2010
Type: article
Abstract: IR in pediatric transplant recipients appears to take longer following MAC and UCBT than following matched sibling allogeneic stem cell transplantation (AlloSCT) (Parkman et al., BBMT, 2006). While RTC prior to AlloSCT is associated with decreased transplant-related morbidity and mortality compared with MAC, effects of RTC on long-term IR in pediatric UCBT recipients are unknown (Satwani, Cairo et al., BBMT, 2005).
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2026616201