Structures and functions associated with the group of mammalian lectins containing collagen‐like sequences
Year: 1989
Type: article
Abstract: The number of proteins found in body fluids and at cell surfaces, which are known to display carbohydrate-binding properties, continues to increase rapidly. In these proteins, in addition to a domain associated with lectin properties, one or more, non-lectin domains are present. It is possible that binding of sugar residues by the lectin domain may be important in triggering a variety of recognition and clearance mechanisms via the non-lectin domains. The group of lectins containing collagen-like sequences may provide some insight into structure/function relationships of the different domains in view of the well defined structures already available for several of these molecules.
Source: FEBS Letters
Authors: Steffen Thiel, Kenneth B.M. Reid
Institution: University of Oxford
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2026745476