Work

Increased ranging depth in optical frequency domain imaging by frequency encoding

Year: 2007

Type: article

Abstract: A technique for increasing the ranging depth in optical frequency domain imaging utilizing frequency encoding is presented. Ranging depth is enhanced by using two interferometer reference arms with different path lengths and independent modulation frequencies (25 and 50 MHz). With this configuration, the sensitivity decreases by 6 dB over a depth range of 7 mm, approximately a threefold improvement over the conventional optical frequency domain imaging technique. We demonstrate that the reference arm frequency separation, tuning speed, center wavelength, and instantaneous coherence length determine the signal-to-cross-talk ratio.

Source: Optics Letters

DOI: 10.1364/ol.32.002768

Authors: S. M. R. Motaghian Nezam, B. J. Vakoc, A. E. Desjardins, G. J. Tearney, B. E. Bouma

Institutions: Harvard University, Massachusetts General Hospital

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Cancer Institute

Awards: G1545476000, Natural History of Vulnerable Coronary Plaques