Work

Contaminant-induced lysosomal membrane damage in blood cells of mussels Mytilus galloprovincialis from the Venice Lagoon:an in vitro study

Year: 1995

Type: article

Abstract: Damage to blood cell lysosomes was investigated in vitro in mussels Mytilus galloprovincialis collected from a series of sites in the Lagoon of Venice, Italy, and correlated with total tissue burdens for a range of contaminants.Retention of the cationic probe neutral red within the lysosomal compartment over time was used as a measure of damage to the lysosomal membrane.Multi-stepwise regression analysis was used to explore the relationship between altered cellular physiology and total body burdens of contaminants.Organochlorines (DDT, HCH and Aroclor 1254), mercury and cobalt were the principle factors involved in evoking pathological responses.

Source: Marine Ecology Progress Series

DOI: 10.3354/meps129189

Authors: DM Lowe, VU Fossato, MH Depledge

Institutions: Plymouth Marine Laboratory, University of Plymouth, National Research Council

Language: English

Topic: Environmental Toxicology and Ecotoxicology

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

SDG: Life below water

Open Access status: bronze

OpenAlex ID: W2027400330