Year: 2004
Type: article
Abstract: In adaptive treatment strategies, the treatment level and type is repeatedly adjusted according to ongoing individual response. Since past treatment may have delayed effects, the development of these treatment strategies is challenging. This paper advocates the use of sequential multiple assignment randomized trials in the development of adaptive treatment strategies. Both a simple ad hoc method for ascertaining sample sizes and simple analysis methods are provided.
Source: Statistics in Medicine
DOI: 10.1002/sim.2022
Author: S. A. Murphy
Institutions: University of Michigan, Institute for Social Research
Language: English
Subfield: Statistics and Probability
Field: Mathematics
Domain: Physical Sciences
Open Access status: bronze
Funder: National Institute on Drug Abuse
OpenAlex ID: W2027795129