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Regulation of Acetylcholinesterase in Neuroblastoma Cells

Year: 1970

Type: article

Abstract: The specific activity of mouse neuroblastoma acetylcholinesterase (EC 3.1.1.7) increased 25-fold when the rate of cell division was restricted. The results show that acetylcholinesterase activity is regulated in neuroblastoma cells and that the regulatory mechanism is inversely related to the rate of cell division. Under the same conditions the specific activity of catechol-O-methyl transferase (EC 2.1.1.6) did not change significantly.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.67.2.786

Authors: A. Blume, F. Gilbert, S. Wilson, J. Farber, R. Rosenberg, M. Nirenberg

Institutions: National Institutes of Health, National Heart, Lung, and Blood Institute

Language: English

Topic: Neuroblastoma Research and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

Open Access status: green

OpenAlex ID: W2027873496

FWCI: 34.82

Cites: 11

Cited by: 226

Related to: 10