Work

Hydrogen peroxide signaling in vascular endothelial cells

Year: 2014

Type: review

Abstract: Redox signaling is implicated in different physiological and pathological events in the vasculature. Among the different reactive oxygen species, hydrogen peroxide (H2O2) is a very good candidate to perform functions as an intracellular messenger in the regulation of several biological events. In this review, we summarize the main physiological sources of H2O2 in the endothelium and the molecular mechanisms by which it is able to act as a signaling mediator in the vasculature.

Source: Redox Biology

DOI: 10.1016/j.redox.2014.02.005

Authors: Rosa Bretón-Romero, Santiago Lamas

Institutions: Consejo Superior de Investigaciones Científicas, Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid

Language: English

Topic: Redox biology and oxidative stress

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $4,310

OpenAlex ID: W2028063897

FWCI: 1.919

Cites: 104

Cited by: 227

Related to: 9