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Family-based association of an ANK3 haplotype with bipolar disorder in Latino populations

Year: 2013
Type: article
Study design: Observational Study
Abstract: Over the past several years, genome-wide association studies (GWAS) have successfully identified genetic loci strongly associated with bipolar disorder (BP). 1 , 2 , 3 Some of the most consistent findings have been in variants located in the ANK3 (ankyrin-G) gene located on chromosome 10q. Schultz et al. 4 found that BP risk alleles in ANK3 , rs9804190 and rs10994336, contributed independently to BP with no significant marker–marker interaction. Subsequent association studies support the ANK3 association in other populations of primarily European or Asian ancestries. 5 , 6 To date, no studies have been reported that focus in Latino populations.
DOI: 10.1038/tp.2013.40
Authors: S D Gonzalez, C Xu, M E Ramirez, J M Zavala, R Armas, S A Contreras, J Contreras, A Dassori, R J Leach, D Flores, A Jerez, H Raventós, A Ontiveros, H Nicolini, M Escamilla
Institutions: Texas Tech University Health Sciences Center, University of California, San Francisco, Langley Porter Psychiatric Hospital and Clinics, The University of Texas at San Antonio Health Science Center, Universidad de Costa Rica, South Texas Veterans Health Care System, University of California, Los Angeles, Los Angeles Medical Center
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $5,290
OpenAlex ID: W2028291571
FWCI: 0.714
Cites: 10
Cited by: 6
Related to: 10