Work

Unified model of hyperthermia via hysteresis heating in systems of interacting magnetic nanoparticles

Year: 2015

Type: article

Abstract: We present a general study of the frequency and magnetic field dependence of the specific heat power produced during field-driven hysteresis cycles in magnetic nanoparticles with relevance to hyperthermia applications in biomedicine. Employing a kinetic Monte-Carlo method with natural time scales allows us to go beyond the assumptions of small driving field amplitudes and negligible inter-particle interactions, which are fundamental to the applicability of the standard approach based on linear response theory. The method captures the superparamagnetic and fully hysteretic regimes and the transition between them. Our results reveal unexpected dipolar interaction-induced enhancement or suppression of the specific heat power, dependent on the intrinsic statistical properties of particles, which cannot be accounted for by the standard theory. Although the actual heating power is difficult to predict because of the effects of interactions, optimum heating is in the transition region between the superparamagnetic and fully hysteretic regimes.

Source: Scientific Reports

DOI: 10.1038/srep09090

Authors: S. Ruta, R. Chantrell, O. Hovorka

Institutions: University of York, University of Southampton

Language: English

Topic: Characterization and Applications of Magnetic Nanoparticles

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,764

Funder: Engineering and Physical Sciences Research Council