Work

Coordinate reduction in cell proliferation and cell death in mouse olfactory epithelium from birth to maturity

Year: 1997

Type: article

Abstract: We investigated cell proliferation and cell death in the olfactory epithelium (OE) of mice from birth to maturity using bromodeoxyuridine and terminal deoxynucleotidyl transferase nick end labeling. We show that cell death events and proliferative activity diminish concomitantly with age in the OE. Thus, the age-dependent and coordinate diminution in cell proliferative activity and cell death events may serve to maintain the thickness of the OE as mice mature and age.

Source: Brain Research

DOI: 10.1016/s0006-8993(97)00467-8

Authors: Kar-Ming Fung, Jan Peringa, Seema Venkatachalam, Virginia M.-Y. Lee, John Q. Trojanowski

Institutions: NYU Langone Health, New York University, University of Groningen, University of Pennsylvania

Language: English

Topic: Neurogenesis and neuroplasticity mechanisms

Subfield: Developmental Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,360